Biofluid mechanics – advanced course

ID: 3266
Course type: scientific and vocational
Course coordinator: Stevanović D. Nevena
Lecturers: Stevanović D. Nevena
Contact: Stevanović D. Nevena
Level of studies: Ph.D. (Doctoral) studies – Mechanical Engineering
ECTS: 5
Final exam type: seminar works

Lectures

Goal

The aim of this subject is getting knowledge about certain class of biological processes from the fluid mechanics point of view and introducing with scientific methods for predicting, analyzing and studying fluid dynamical processes in the human body.

Outcome

Students are qualifying for computing and analyzing by themself biofluid flow processes with contemporary and scientific methods. Also, they obtain the ability to apply these concepts appropriately for modeling biofluid flow in blood vessels, kidneys, lungs and joints.

Theoretical teaching

Theoretical lessons incorporates: understanding of biofluid properties and applications of the fundamental laws (mass, momentum, and energy) that govern fluid mechanics to solve biofluid flow such as those in the cardiovascular system, introducing with basic non-Newtonian fluid models especially rheology of biofluids which are present in the human body, introducing with cardiovascular system and related diseases, circulatory system, steady and unsteady biological flows and wave propagation theory and oscillatory flow, defining velocity, pressure and flow rate in the blood vessels, modelling blood flow and diffusion process in kidneys, diffusion process in haemodialyser, blood and air flows in the lungs, joint friction, as well as modelling hydrodynamic separation of particles and cells, and hydrodynamic phenomena in drug-delivery systems.

Practical teaching

Practical lessons contains applications of the basic fluid mechanics equations to solve biofluid flows such as: creating and solving mathematical models for blood vessels flow, solving models for stationary blood flow in rigid and elastic blood vessels, modeling pulsating fluid flow, calculation of the pressure wave propagation, calculation of the velocity, pressure and flow rate in blood vessels, modeling and calculating diffusion process among blood vessels walls and tissues and application on the haemodialys process and renal flow.

Attendance requirement

Passed exams in Fluid Mechanics.

Resources

Course handouts.

Assigned hours

Total assigned hours: 65

Active teaching (theoretical)

New material: 45
Elaboration and examples (recapitulation): 5

Active teaching (practical)

Auditory exercises: 0
Laboratory exercises: 0
Calculation tasks: 0
Seminar paper: 0
Project: 0
Consultations: 0
Discussion/workshop: 0
Research study work: 0

Knowledge test

Review and grading of calculation tasks: 0
Review and grading of lab reports: 0
Review and grading of seminar papers: 10
Review and grading of the project: 0
Test: 0
Test: 0
Final exam: 5

Knowledge test (100 points total)

Activity during lectures: 10
Test/test: 0
Laboratory practice: 0
Calculation tasks: 0
Seminar paper: 50
Project: 0
Final exam: 40
Requirement for taking the exam (required number of points): 50

Literature

Waite L., Fine J., Applied Biofluid Mechanics, 2007, MsGraw-Hill, ISBN: 9780071509510; Mazumdar, N.J., Biofluid Mechanics, World Scientific, 1992, ISBN:9810209274; Kleinstreuer, C., Biofluid Dynamics, Principles and Selected Applications, CRC Press, 2016, ISBN: 9780849322211; Fung, Y.C., Biomechanics Motion, Flow, Stress and Growth, Springer-Verlag, 1990, ISBN: 978-0-387-97124-7